EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Overview | 5-nitroguaiacol sodium, soluble in methanol, ethanol, acetone and other organic solvents, storage Stability under conventional conditions. 5-nitroguaiacol sodium and O-nitrophenol sodium, P-nitrophenol sodium compound preparation of sodium nitrophenol, also known as high-yield, extra, such as goods have 0.9%, 1.4%, 1.8%, or 1.6% of the water, it has been widely used in agriculture. The compound sodium nitrophenolate is the first high-efficiency plant growth regulation discovered in Japan in the sixties of the 20th century. The Japanese trade name is aidopao, and the product dosage form is 1.8% of the compound sodium nitrophenolate agent, which can be diluted by 2000-6000 times, and the actual commonly used concentration is 3-10ppm, equivalent to the amount of 0.2-0.4 grams per mu, that is, there is a significant effect of increasing production, so the compound of sodium nitrate is called the magic material. |
Application | sodium 5-nitroguaiacolate is the most active monomer in compound sodium nitrophenate, it and its compound preparation compound sodium nitrophenolate (with O-nitrate, on-nitrate, etc.), has been designated by the United Nations Food and Agriculture Organization (FAO) recommended as green food engineering plant growth regulator. It is widely used in food crops, cash crops, oil crops, vegetables, fruits, fruit trees, cotton, flowers, forests, vegetation and so on. Application in fertilizer, pesticides, fungicides, Seed Coating Agent has a very obvious synergistic effect; Application in animal husbandry, fisheries, can significantly improve the meat, eggs, wool, the yield and quality of the skin, but also can enhance the immune ability of animals, prevent a variety of diseases. At present, the product and its compound preparation have been widely used in China and other countries and regions. |
preparation | (1) guaiacol was prepared by Direct Nitration with mixed acid or concentrated nitric acid. Because guaiacol contains-OH and-OCH3, both of which are strong ortho-and para-positioning groups, the products obtained are 4-nitroguaiacol, 5-nitroguaiacol, A mixture of 6-nitroguaiacol. This process is simple and easy to control, but because of the more by-products and difficult to separate and rarely used. (2)2, 3-dimethoxy-5-nitrophenol and saturated hydrobromic acid solution were prepared under mild reaction conditions. (3)2-methoxy-(1,4) oxime quinone is prepared by reacting with potassium ferricyanide under alkaline conditions. The reaction steps are simple with few by-products. (4) nitroanisole was prepared by electrolysis in an electrolytic cell equipped with a stainless steel electrode using an acidified CH3CN-H2O mixture as a solvent. The highest yield of the process is only 31.4%, and the by-products of p-nitrophenol and p-methoxyphenol account for about 2%. 49.1% is the raw material which is not reacted, the production cost is high, and it is not easy to control. |
toxicity | Acute oral LD50 of 5-nitroguaiacol sodium in female and male rats were 3100 and 1270mg/kg, respectively, no irritation to eyes and skin. |
Use | biochemical studies A Cell Activator |